Caleb Davis Bradham was born May 27, 1867 to George Washington and Julia McCann Bradham in Chinquapin, North Carolina. Bradham was of English and Scotch-Irish descent. He was an American pharmacist, best known as the inventor of Pepsi.

He graduated from the University of North Carolina at Chapel Hill where he was a member of the Philanthropic Society, and attended the University of Maryland School of Medicine.

Circa 1890, he dropped out of the University of Maryland School of Medicine, owing to his father's business going bankrupt. After returning to North Carolina, he was a public school teacher for about a year, and soon thereafter opened a drug store in New Bern named the "Bradham Drug Company" that, like many other drug stores of the time, also housed a soda fountain.

Middle Street and Pollock Street in downtown New Bern, is where Bradham, in 1893, invented the recipe—a blend of kola nut extract, vanilla, and "rare oils"—for what was initially known as "Brad's Drink," but on August 28, 1898 was renamed Pepsi-Cola.Bradham named his drink after a combination of the terms “pepsin” and “cola,” as he believed that his drink aided digestion much like the pepsin enzyme does, even though it was not used as an ingredient. His assistant James Henry King was the first to taste the new drink.

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