Who played the female lead alongside of Jim Carey in the film "Me, Myself & Irene"?

"Me, Myself & Irene" is a 2000 American dark comedy drama film directed by the Farrelly brothers, and starring Jim Carrey and Renée Zellweger. The film is about a Rhode Island state trooper named Charlie who, after years of continuously suppressing his rage and feelings, suffers a psychotic breakdown that results in a second personality, Hank.

Charlie Baileygates (Jim Carrey) is a veteran Rhode Island state trooper who has been taken advantage of by those around him, including his ex-wife Layla (Traylor Howard). Believing that Charlie needs a vacation, his commanding officer (Robert Forster) orders him to escort Irene Waters (Renée Zellweger) from Rhode Island to Massena, New York, because she reportedly committed a hit-and-run.

Renée Kathleen Zellweger (born April 25, 1969) is an American actress and producer. She is the recipient of numerous accolades, including an Academy Award and three Golden Globe Awards. Zellweger was one of the highest-paid actresses in the world by 2007 and was named Hasty Pudding's Woman of the Year in 2009.