Sir Christopher Wren is one of the most highly acclaimed English architects in history. He was accorded responsibility for rebuilding 52 churches in the City of London after the Great Fire in 1666, including what is regarded as his masterpiece, St. Paul's Cathedral, on Ludgate Hill, completed in 1710.

St. Paul's Cathedral took thirty-five years to build. The most dramatic aspect of St. Paul's was its great dome. It was the second largest dome ever built (the largest was St. Peter's Basilica in Rome). Both domes were based on the one in the Pantheon built by the ancient Romans.

Wren was sixty-six years old when he finished St. Paul's. Other buildings designed by Wren included the Royal Exchange, College of Physicians, Chelsea Hospital, the Royal Naval College, Custom House and the Drury Lane Theatre. When Christopher Wren died in 1723 he became the first person to be buried in St. Paul's Cathedral.

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