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During fever, why do we feel cold when our body temperature rises?

Anyone who has ever had the flu knows that fever isn’t uncomfortable because you feel hot – it’s uncomfortable because you feel freezing cold. You get goosebumps, you’re shivering, you’re piling on the covers.

Fever, also known as pyrexia, is defined as an elevation in body temperature above the normal range due to an increase in the body’s natural set point. Most people associate fever with infections, but fever can also frequently occur with autoimmune diseases, cancer, drug reactions, and even blood clots. Fever is not a direct result of these conditions, but rather a consequence of triggering the body’s inflammatory pathways. One key member of this inflammatory cascade is a group of molecules called pyrogens, which directly interact with the hypothalamus in the brain to produce fever.

Thy hypothalamus serves as the body’s thermostat. When triggered by pyrogens, the hypothalamus tells the body to generate heat by inducing shivering, goosebumps, and constriction of blood vessels near the surface of the skin. It even causes a subjective feeling of cold, which encourages behavioral responses to raise the body temperature, like reaching for the covers. All of these things are adaptive when your body temperature falls below its usual set-point (about 37 degrees Celsius), which typically occurs in cold weather. But they become abnormal in the setting of fever, when your hypothalamus signals to the body to raise its temperature well above the normal range.

If pyrogens suddenly disappear from the bloodstream, as is the case with intermittent fevers, the hypothalamus all of a sudden senses that things are way too hot, and tells the body to kick in its usual cooling-off mechanisms. That’s why people sweat profusely when their fever “breaks.”


This information was taken from Quora. Click here to view the original post.

Do you always feel cold during fever? Tell us in the comments below!

#health #Quora

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What are your thoughts on this subject?
16 Comments
Player
Thanks for the info.
0
Sep 24, 2019 5:15PM
Cheryl McMeekin
Great info
0
Jul 22, 2019 9:11AM
Shambhu Sah
very informative.
1
Jul 2, 2019 11:46PM
vasily tchaikovsky
Good Q and information,thanks
0
Jan 13, 2019 10:17PM
Lynne Cage
Informative, thnx
0
Jan 4, 2019 12:22AM
Carmelina Piperni
VERY INTERESTING............
0
Jan 3, 2019 7:19PM
lilysvn
Thank you
0
Sep 11, 2018 6:58PM
Diana Newman
I had diverticulosis a while ago and had a fever and got uncontrollable shivers. I felt absolutely dreadful.
0
Jul 30, 2018 5:35AM
ninakamwene
Thank you very educational trivia. Keep them coming Quiz Folks.
1
Jul 26, 2018 5:46PM
Julie Anne Bunker
That’s how I know I have a fever,when I get uncontrollable chills.
1
Jul 9, 2018 8:05PM
John Puza
That’s a terrible feeling!!!
1
Jul 3, 2018 8:53AM
Linda Spreng
Yep, knew that stuff.
1
Jul 2, 2018 5:01PM
Connie Hurley
Very interesting!
0
Jul 1, 2018 4:35PM
scottlarock
Laura Herendeen, me too...
0
Jun 29, 2018 8:39PM
scottlarock
wash your hands...drink water...avoid sick people...at all costs...
0
Jun 29, 2018 8:39PM

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